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Hyperion DeFi Inc. (HYPD) reported fourth-quarter revenue of $496,229, representing a 64% increase from the third quarter’s $302,506, according to the company’s financial results released today.
The company’s adjusted gross profit grew 87% quarter-over-quarter from $439,386 in Q3 2025 to $820,997 in Q4 2025. For the full year 2025, revenue increased to $813,455 from $57,336 in 2024.
Hyperion DeFi operates five business lines focused on the Hyperliquid blockchain ecosystem, including staking yield, validator commissions, yield enhancement, DeFi monetization, and ecosystem rewards. The company’s treasury holds 1.93 million HYPE tokens as of March 23, 2026.
The company reported a net loss of $39.8 million for Q4 2025, compared to net income of $6.6 million in Q3 2025. The annual net loss decreased to $45.3 million in 2025 from $49.8 million in 2024.
Operating expenses excluding stock-based compensation declined 30% quarter-over-quarter from $4.3 million to $3.0 million. Research and development expenses fell 49% to $189,000 in Q4 from $374,000 in Q3.
The company’s gross HYPE holdings decreased from $77.8 million at the end of Q3 to $47.8 million at the end of Q4, reflecting the decline in HYPE token price from $45.19 to $25.43 during the period.
Hyperion DeFi announced it executed a letter of intent to monetize its Optejet medical device, with potential closing in Q2 2026. The company provides guidance of $4 million to $6 million in adjusted gross profit for 2026.
