Denali Therapeutics Inc (DNLI)

Currency in USD
20.88
+0.72(+3.57%)
Real-time Data·
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Fair Value
Day's Range
20.2021.05
52 wk Range
12.3123.77
Key Statistics
Prev. Close
20.16
Open
20.24
Day's Range
20.2-21.05
52 wk Range
12.31-23.77
Volume
518.55K
Average Vol. (3m)
1.78M
1-Year Change
53.0752%
Book Value / Share
6.49
Fair Value
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Fair Value Upside
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DNLI Scorecardpro icon
Company’s Health
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Fair Value
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Fair Price
Upside
Price Target
36.21
Upside
+73.44%
Members' Sentiments
Bearish
Bullish
ProTips
4 analysts have revised their earnings upwards for the upcoming period

Denali Therapeutics Inc News & Analysis

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Technical Analysis

Summary
Strong Sell
Sell
Neutral
Buy
Strong Buy
Strong Buy
Technical Indicators
Strong Buy
Moving Averages
Strong Buy

Denali Therapeutics Inc., a biopharmaceutical company, discovers and develops therapeutics to treat neurodegenerative and lysosomal storage diseases. The company develops Eclitasertib (SAR443122/DNL758) RIPK1 inhibitor program for peripheral inflammatory diseases; BIIB122/DNL151 LRRK2 inhibitor program for Parkinson's disease; TAK-594/DNL593 program for frontotemporal dementia-granulin; DNL126 program for MPS IIIA (Sanfilippo Syndrome A); and DNL310 Tividenofusp alfa, an enzyme replacement therapy program for MPS II (Hunter Syndrome). Its Enzyme TransportVehicle (TV) programs include DNL952 for the treatment of Pompe disease; DNL111 for Parkinson’s and Gaucher diseases; and DNL622 for Hurler syndrome (MPS I). The company’s OTV programs also comprise DNL628 targeting tau for Alzheimer’s disease; and DNL422 targeting alpha synuclein for Parkinson’s disease, as well as antibody TV program includes DNL921 targeting Abeta for treating Alzheimer’s disease. The company was formerly known as SPR Pharma Inc. and changed its name to Denali Therapeutics Inc. in March 2015. Denali Therapeutics Inc. was incorporated in 2013 and is headquartered in South San Francisco, California.

Compare DNLI to Peers and Sector

Metrics to compare
DNLI
Peers
Sector
Relationship
P/E Ratio
−6.4x−2.4x−0.5x
PEG Ratio
0.400.150.00
Price / Book
3.3x7.3x2.6x
Price / LTM Sales
-11.4x3.2x
Upside (Analyst Target)
95.9%68.5%47.6%
Fair Value Upside
Unlock4.2%6.1%Unlock

Analyst Ratings

18 Buy
1 Hold
0 Sell
Ratings:
19 analysts
Overall Consensus
Strong Buy

Analysts 12-Month Price Target:

Average 36.21
(+73.44% Upside)
Firm
ArticlePositionPrice TargetUpside / DownsideFrom Price TargetActionDate
Baird
Buy34.00+62.76%32.00MaintainApr 07, 2026
BTIG
Buy39.00+86.69%38.00MaintainApr 06, 2026
BofA Securities
Buy31.00+48.40%29.00MaintainMar 26, 2026
H.C. Wainwright
Buy42.00+101.05%32.00MaintainMar 26, 2026
Morgan Stanley
Buy42.00+101.05%40.00MaintainMar 26, 2026

Earnings

Latest Release
Feb 26, 2026
EPS / Forecast
-0.73 / -0.75
Revenue / Forecast
-- / 6.92M
EPS Revisions
Last 90 days

DNLI Income Statement

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FAQ

What Is the Denali Therapeutics (DNLI) Stock Price Today?

The Denali Therapeutics stock price today is 20.88 USD.

What Stock Exchange Does Denali Therapeutics Trade On?

Denali Therapeutics is listed and trades on the Nasdaq Stock Exchange.

What Is the Stock Symbol for Denali Therapeutics?

The stock symbol for Denali Therapeutics is "DNLI."

What Is the Denali Therapeutics Market Cap?

As of today, Denali Therapeutics market cap is 3.31B USD.

What Is Denali Therapeutics's Earnings Per Share (TTM)?

The Denali Therapeutics EPS (TTM) is -2.97.

When Is the Next Denali Therapeutics Earnings Date?

Denali Therapeutics will release its next earnings report on May 12, 2026.

From a Technical Analysis Perspective, Is DNLI a Buy or Sell?

Based on moving averages and other technical indicators, the daily buy/sell signal is Strong Buy.

How Many Times Has Denali Therapeutics Stock Split?

Denali Therapeutics has split 0 times.

How Many Employees Does Denali Therapeutics Have?

Denali Therapeutics has 503 employees.

What is the current trading status of Denali Therapeutics (DNLI)?

As of Apr 15, 2026, Denali Therapeutics (DNLI) is trading at a price of 20.88 USD, with a previous close of 20.16 USD. The stock has fluctuated within a day range of 20.20 USD to 21.05 USD, while its 52-week range spans from 12.31 USD to 23.77 USD.

What Is Denali Therapeutics (DNLI) Price Target According to Analysts?

The average 12-month price target for Denali Therapeutics is 36.21 USD, with a high estimate of 42 USD and a low estimate of 25 USD. 18 analysts recommend buying the stock, while 0 suggest selling, leading to an overall rating of Strong Buy. The stock has an +73.44% Upside potential.

What Is the DNLI Premarket Price?

DNLI's last pre-market stock price is 20.50 USD. The pre-market share volume is 2,720.00, and the stock has decreased by 0.34, or 1.69%.

What Is the DNLI After Hours Price?

DNLI's last after hours stock price is 20.17 USD, the stock has decreased by 0.01, or 0.05%.
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